Impact of bone scintigraphy on the clinical management of a patient with sickle cell anemia and recent chest pain

Clin Nucl Med. 1996 Jul;21(7):523-6. doi: 10.1097/00003072-199607000-00002.


The authors present a cases of acute chest syndrome that was originally thought to be due to pneumonia, in which bone imaging obtained 4 weeks later for knee pain showed a secondary finding of multiple rib infarcts that clarified the etiology of the patient's chest manifestations and led to a change in the management of the patient. Bone scintigraphy should be considered in the work-up of patients with sickle cell anemia and concurrent chest symptoms.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anemia, Sickle Cell / complications*
  • Bone and Bones / diagnostic imaging
  • Chest Pain / diagnostic imaging
  • Chest Pain / etiology*
  • Diagnosis, Differential
  • Female
  • Gallium Radioisotopes
  • Humans
  • Infarction / diagnostic imaging*
  • Infarction / etiology*
  • Pneumonia / diagnostic imaging
  • Radionuclide Imaging
  • Ribs / blood supply*
  • Ribs / diagnostic imaging
  • Technetium Tc 99m Medronate


  • Gallium Radioisotopes
  • Technetium Tc 99m Medronate