EDTA chelation therapy in the treatment of vascular disease

J Cardiovasc Nurs. 1996 Apr;10(3):78-86. doi: 10.1097/00005082-199604000-00008.


Ethylenediamine tetraacetic acid (EDTA) chelation therapy has been used for decades for the treatment of vascular disease, alone or in combination with other treatments. This article includes a historic review of the research literature, current evidence of effectiveness, potential mechanisms of action of EDTA, and some brief case reports. The authors conclude that EDTA chelation therapy is a valuable therapeutic option for vascular disease, either alone or in conjunction with standard treatment protocols.

Publication types

  • Review

MeSH terms

  • Chelating Agents / therapeutic use*
  • Chelation Therapy*
  • Complementary Therapies
  • Edetic Acid / therapeutic use*
  • Humans
  • Vascular Diseases / drug therapy*


  • Chelating Agents
  • Edetic Acid