Dramatic decrease in tuberculin skin test conversion rate among employees at a hospital in New York City

Am J Infect Control. 1995 Dec;23(6):352-6. doi: 10.1016/0196-6553(95)90265-1.


Background: The Centers for Disease Control and Prevention recently issued updated guidelines for preventing the transmission of tuberculosis in health care facilities. Many recommendations, including the use of high-efficiency particulate air filter respirators, are expensive to implement and of unproven efficacy. We therefore reviewed the tuberculin skin test conversion rate among our employees from 1991 to 1993, before introduction of high-efficiency particulate air filter respirators. During this period, several other improvements in tuberculosis control were implemented.

Methods: Employee tuberculin test conversion rates were reviewed by 6-month interval from 1991 to 1993.

Results: Throughout the study period, several tuberculosis control measures were implemented, including early isolation of patients with suspected cases of tuberculosis in rooms with negative-pressure ventilation, placement of germicidal UV light fixtures into patient rooms and common areas, and use of Technol shields (Technol, Inc., Fort Worth, Texas) (1991), particulate respirators (1992), and dust-mist-fume respirators (1993). With these improvements, the conversion rate among employees fell from 20.7% in the first 6 months of 1991 to 5.8% in the latter half of 1993.

Conclusions: The rate of skin test conversion among our employees decreased before introduction of high-efficiency particulate air filter respirators. This suggests that nosocomial spread of tuberculosis can be decreased by means of previously established, less costly methods.

Publication types

  • Comparative Study

MeSH terms

  • Cross Infection / prevention & control*
  • Female
  • Guidelines as Topic
  • Health Plan Implementation
  • Humans
  • Infection Control / methods*
  • Male
  • New York City
  • Patient Isolation
  • Personnel, Hospital / statistics & numerical data*
  • Tuberculin Test / statistics & numerical data*
  • Tuberculosis / prevention & control*
  • Tuberculosis, Pulmonary / prevention & control
  • Ultraviolet Rays
  • Ventilators, Negative-Pressure