Exposure to and activation of dietary heterocyclic amines in humans

Crit Rev Oncol Hematol. 1995 Nov;21(1-3):19-31. doi: 10.1016/1040-8428(95)00178-6.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Availability
  • Biotransformation
  • Carcinogens / adverse effects
  • Carcinogens / analysis
  • Carcinogens / pharmacokinetics*
  • Colorectal Neoplasms / chemically induced
  • Cooking
  • Cytochrome P-450 CYP1A2 / metabolism
  • DNA Adducts
  • Diet* / adverse effects
  • Heterocyclic Compounds / adverse effects
  • Heterocyclic Compounds / analysis
  • Heterocyclic Compounds / pharmacokinetics*
  • Hot Temperature
  • Humans
  • Imidazoles / adverse effects
  • Imidazoles / analysis
  • Imidazoles / pharmacokinetics*
  • Liver / metabolism
  • Meat / analysis
  • Mutagenicity Tests
  • Mutagens / adverse effects
  • Mutagens / analysis
  • Mutagens / pharmacokinetics*
  • Proteins / metabolism
  • Quinolines / adverse effects
  • Quinolines / analysis
  • Quinolines / pharmacokinetics*
  • Quinoxalines / adverse effects
  • Quinoxalines / analysis
  • Quinoxalines / pharmacokinetics*
  • Rats
  • Risk Assessment

Substances

  • Carcinogens
  • DNA Adducts
  • Heterocyclic Compounds
  • Imidazoles
  • Mutagens
  • Proteins
  • Quinolines
  • Quinoxalines
  • 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline
  • 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
  • Cytochrome P-450 CYP1A2
  • 2-amino-3,4-dimethylimidazo(4,5-f)quinoline