Comparative efficacy of four Ayurvedic formulations in the treatment of acne vulgaris: a double-blind randomised placebo-controlled clinical evaluation

J Ethnopharmacol. 1995 Dec 15;49(3):127-32. doi: 10.1016/0378-8741(95)01309-1.


Eighty-two patients with acne vulgaris were randomised into five groups. Four different Ayurvedic treatment schedules were given orally for 6 weeks, while one group received a placebo. Physical and clinical investigations were carried out at 2 week intervals. A significant reduction in lesion count was observed in patients receiving Sunder Vati when compared with the placebo and the other Ayurvedic formulations, which failed to produce any significant difference from the pretreatment condition. The drug therapies were well tolerated.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Acne Vulgaris / drug therapy*
  • Adult
  • Double-Blind Method
  • Female
  • Humans
  • India
  • Male
  • Medicine, Ayurvedic*
  • Minerals / therapeutic use
  • Plant Extracts / therapeutic use*
  • Plants, Medicinal


  • Minerals
  • Plant Extracts