Adenovirus Mixture Isolated From the Brain of an AIDS Patient With Encephalitis

J Med Virol. 1995 Oct;47(2):168-71. doi: 10.1002/jmv.1890470210.

Abstract

A mixture of adenoviruses 31 and 49 was isolated from the brain of an AIDS patient with encephalitis. Adenovirus hexon protein was detected in neurons by indirect immunofluorescence. By restriction endonuclease analysis both adenovirus 31 and 49 were shown to be new genotypes. This is the first report of the isolation of a mixture of adenoviruses from adenovirus encephalitis and the first association of adenovirus 49, a new candidate serotype, with encephalitis.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / complications
  • AIDS-Related Opportunistic Infections / virology*
  • Adenovirus Infections, Human / complications
  • Adenovirus Infections, Human / virology*
  • Adenoviruses, Human / classification
  • Adenoviruses, Human / isolation & purification*
  • Antigens, Viral / immunology
  • Brain / pathology
  • Brain / virology
  • Capsid / immunology
  • Capsid Proteins*
  • Cell Line
  • Encephalitis, Viral / complications
  • Encephalitis, Viral / virology*
  • Fatal Outcome
  • Female
  • Genotype
  • Humans
  • Middle Aged
  • Serotyping
  • Tumor Cells, Cultured

Substances

  • Antigens, Viral
  • Capsid Proteins
  • hexon capsid protein, Adenovirus