Drug-dependent exercise-induced anaphylaxis

Allergy. 1995 Dec;50(12):992-4. doi: 10.1111/j.1398-9995.1995.tb02514.x.


Exercise-induced anaphylaxis (EIA) is well known and may be food-dependent. We describe a patient with a history of anaphylaxis during exercise after taking nafylpropion acid (Naprosyne), a nonsteroidal anti-inflammatory drug. An exercise-challenge test after Naprosyne intake induced bronchoconstriction. The combination of history and challenge tests suggests that intolerance or allergy to drugs may present as EIA.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anaphylaxis / chemically induced
  • Anaphylaxis / etiology*
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Exercise*
  • Female
  • Humans
  • Naproxen / adverse effects*


  • Anti-Inflammatory Agents, Non-Steroidal
  • Naproxen