Cervical chymopapain nucleolysis: MR imaging assessment of chymopapain efficacy

Neurosurg Clin N Am. 1996 Jan;7(1):1-16.


Soft cervical disc herniations can be treated by minimally invasive procedures with excellent results. Chemonucleolysis with chymopapain is one alternative to surgery that is shown to be innocuous within a strict technical framework. MR imaging allows an accurate diagnosis of the cause of cervical root compression, thus facilitating the choice of conventional surgery or minimally invasive procedures.

MeSH terms

  • Adult
  • Cervical Vertebrae / diagnostic imaging
  • Cervical Vertebrae / drug effects*
  • Cervical Vertebrae / pathology*
  • Chymopapain / therapeutic use*
  • Equipment and Supplies
  • Follow-Up Studies
  • Humans
  • Intervertebral Disc Chemolysis* / instrumentation
  • Intervertebral Disc Chemolysis* / methods
  • Intervertebral Disc Displacement / pathology*
  • Intervertebral Disc Displacement / therapy*
  • Magnetic Resonance Imaging*
  • Middle Aged
  • Prospective Studies
  • Tomography, X-Ray Computed
  • Treatment Outcome


  • Chymopapain