Adult respiratory distress syndrome induced by a Chinese medicine, Kamisyoyo-san

Intern Med. 1996 Jun;35(6):494-6. doi: 10.2169/internalmedicine.35.494.

Abstract

We report the first case of Kamisyoyo-san-induced adult respiratory distress syndrome (ARDS). A 59-year-old female was given Kamisyoyo-san for treatment of seborrheic dermatitis. She then presented with a respiratory illness having clinical, radiologic and functional characteristics of ARDS. Bronchoalveolar lavage fluid showed an increased number of lymphocytes, neutrophils and eosinophils. The lymphocyte stimulation test with Kamisyoyo-san was positive.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Bupleurum
  • CD4-CD8 Ratio
  • Dermatitis, Seborrheic / drug therapy
  • Drugs, Chinese Herbal / adverse effects*
  • Drugs, Chinese Herbal / pharmacology
  • Female
  • Humans
  • Lung Diseases, Interstitial / chemically induced
  • Lymphocyte Activation / drug effects
  • Middle Aged
  • Plant Extracts / adverse effects*
  • Plant Extracts / pharmacology
  • Pulmonary Edema / chemically induced
  • Pulmonary Eosinophilia / chemically induced*
  • Respiratory Distress Syndrome / chemically induced*

Substances

  • Bupleurum root extract
  • Drugs, Chinese Herbal
  • Plant Extracts
  • kamisyoyo san