RNA splicing: unexpected spliceosome diversity

Curr Biol. 1996 Jul 1;6(7):802-5. doi: 10.1016/s0960-9822(02)00599-7.


A novel form of spliceosome, containing the minor snRNPs U11 and U12, splices a class of pre-mRNA introns with non-consensus splice sites. This unexpected spliceosome diversity has interesting implications for the evolution and expression of eukaryotic genes.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Introns*
  • Nuclear Proteins / genetics*
  • RNA Precursors*
  • RNA Splicing*
  • Ribonucleoproteins, Small Nuclear / metabolism*
  • Spliceosomes
  • tRNA Methyltransferases


  • Nuclear Proteins
  • RNA Precursors
  • Ribonucleoproteins, Small Nuclear
  • U11 small nuclear ribonucleoprotein, human
  • U11-U12 small nuclear ribonucleoprotein
  • NOP2 protein, human
  • tRNA Methyltransferases