Novel tetranucleotide repeat polymorphism in the human adenosine deaminase gene: interethnic comparison of three major human groups

R Scozzari; F Cruciani; P Santolamazza; E Parra; D Sellitto; D Modiano; G Meloni; W Cai; P Moral

Novel tetranucleotide repeat polymorphism in the human adenosine deaminase gene: interethnic comparison of three major human groups

Hum Biol. 1996 Apr;68(2):315-20.

Authors

R Scozzari¹, F Cruciani, P Santolamazza, E Parra, D Sellitto, D Modiano, G Meloni, W Cai, P Moral

Affiliation

¹ Dipartimento di Genetica e Biologia Molecolare, Università La Sapienza, Rome, Italy.

PMID: 8838919

Abstract

A new tetranucleotide repeat polymorphism was revealed at the human adenosine deaminase (ADA) locus by using the polymerase chain reaction and denaturing polyacrylamide gel electrophoresis. Allele frequencies were estimated in seven populations from three major ethnic groups. Heterozygosity values were calculated and found to differ significantly between Africans and non-Africans.

Publication types

Multicenter Study

MeSH terms

Adenosine Deaminase / analysis
Adenosine Deaminase / genetics*
Base Sequence
Ethnicity / genetics*
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic / genetics*
Population*

Substances

Adenosine Deaminase