Improved outcome for infants at the limits of viability

Eur J Pediatr. 1996 Aug;155(8):665-7. doi: 10.1007/BF01957149.


Factors associated with survival and freedom from cerebral parenchymal lesions and severe retinopathy were examined in a cohort of 250 extremely preterm infants of less than 26 weeks gestation admitted to a regional neonatal intensive care unit between 1982 and 1993. There were 99 survivors of whom 73 were free of major early morbidity.

Conclusion: Logistic regression showed that both survival and survival free from early morbidity were independently related to gestation, birth weight, birth period and antenatal steroid prophylaxis.

MeSH terms

  • Birth Weight
  • Female
  • Gestational Age
  • Humans
  • Infant Mortality / trends*
  • Infant, Newborn
  • Infant, Premature*
  • Intensive Care Units, Neonatal
  • Logistic Models
  • Male
  • Outcome Assessment, Health Care
  • Retinopathy of Prematurity / epidemiology
  • Steroids / administration & dosage
  • Survival Analysis


  • Steroids