Validity of the Hamilton Rating Scale for depression

Br J Psychiatry. 1977 Jul:131:49-52. doi: 10.1192/bjp.131.1.49.


In 26 depressed patients, a high correlation (0-89) was found between the Hamilton score and a psychiatrist's global rating and between the change (0-68) in these ratings during treatment. The Hamilton scale was able to differentiate at the o-01 level four degrees of severity based on the global rating. Limiting the range of severity measured was found to lower significantly the correlation between the ratings. A prospective examination of a six-item sub-scale of the Hamilton scale developed by Beck and associates failed to confirm its claimed improvement in sensitivity or validity.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Depression / diagnosis*
  • Humans
  • Psychiatric Status Rating Scales*
  • Statistics as Topic