Carbamazepine for combativeness in acute traumatic brain injury

J Neuropsychiatry Clin Neurosci. Winter 1996;8(1):96-9. doi: 10.1176/jnp.8.1.96.


Psychiatrists increasingly consult on the treatment of acute traumatic brain injury (TBI) when combativeness compromises safe critical care. The author discusses use of carbamazepine for 7 combative patients with multiple trauma including TBI. This cohort had a clinical decrease in combativeness within 4 days after carbamazepine, compared with this Level I trauma center's experience of prolonged combative periods without its use.

Publication types

  • Case Reports

MeSH terms

  • Accidents, Traffic
  • Adult
  • Aggression / drug effects*
  • Brain Injuries / complications
  • Brain Injuries / psychology*
  • Carbamazepine / therapeutic use*
  • Critical Care
  • Female
  • Humans
  • Male
  • Multiple Trauma / psychology
  • Skiing / injuries


  • Carbamazepine