Safety of tetanus toxoid in pregnant women: a hospital-based case-control study of congenital anomalies

Bull World Health Organ. 1995;73(5):605-8.


Reported are the results of the Latin American Collaborative Study of Congenital Malformations (ECLAMC), a hospital-based case-control study of 34,293 malformed and 34,477 matched nonmalformed newborn controls. No statistical differences were found between the malformed and control groups, exposed or not exposed to tetanus toxoid.

Publication types

  • Multicenter Study

MeSH terms

  • Abnormalities, Drug-Induced / etiology*
  • Adverse Drug Reaction Reporting Systems
  • Case-Control Studies
  • Female
  • Humans
  • Pregnancy
  • Prenatal Exposure Delayed Effects*
  • Risk Factors
  • South America
  • Tetanus Toxoid / adverse effects*


  • Tetanus Toxoid