The molecular control mechanisms of meiosis in fission yeast

Trends Biochem Sci. 1996 Jan;21(1):18-22.


Recent experiments have shown that the inactivation of a protein kinase, pat1, and the activation of an RNA-binding protein, mei2, commit fission yeast cells to enter meiosis. Both the cyclic AMP cascade and the mitogen-activated protein kinase cascade seem to be involved in this activation/inactivation. An RNA molecule that cooperates with mei2 to play a critical role in the promotion of meiosis I has also been identified.

Publication types

  • Review

MeSH terms

  • Fungal Proteins / genetics*
  • Meiosis / genetics
  • RNA, Fungal / genetics*
  • RNA-Binding Proteins / genetics*
  • Schizosaccharomyces / genetics
  • Schizosaccharomyces / growth & development*
  • Schizosaccharomyces pombe Proteins*


  • Fungal Proteins
  • RNA, Fungal
  • RNA-Binding Proteins
  • Schizosaccharomyces pombe Proteins
  • mei2 protein, S pombe