Desquamative interstitial pneumonia-like reaction accompanying pulmonary lesions

Chest. 1977 Aug;72(2):166-9. doi: 10.1378/chest.72.2.166.


Six patients with specific pulmonary diseases had pulmonary tissue surgically resected for diagnostic purposes. All six cases were characterized by space-occupying lesions surrounded by a peculiar reaction of the pulmonary parenchyma indistinguishable from desquamative interstitial pneumonia. If small biopsies from these areas had been taken, a diagnosis of desquamative interstitial pneumonia would have been made, and the underlying process would have gone undetected. These cases corroborate even further the concept that desquamative interstitial pneumonia is a pattern of pulmonary reaction, rather than a well-defined disease entity. Furthermore, it seems advisable to make the dianosis of desquamative interstitial pneumonia only when other conditions have been carefully ruled out by thorough clinical and pathologic investigations.

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Diagnostic Techniques, Surgical
  • Female
  • Humans
  • Lung Diseases / diagnosis
  • Lung Diseases / diagnostic imaging
  • Lung Diseases / pathology*
  • Male
  • Middle Aged
  • Pulmonary Alveoli / pathology*
  • Pulmonary Alveoli / ultrastructure
  • Pulmonary Fibrosis / diagnosis
  • Pulmonary Fibrosis / diagnostic imaging
  • Pulmonary Fibrosis / pathology*
  • Radiography