Measles immunization in children with a history of egg allergy

Vaccine. 1996 Feb;14(2):131-4. doi: 10.1016/0264-410x(95)00154-s.


This study investigated the use of measles vaccine in children with a history of egg protein hypersensitivity, referred between 1987 and 1993 to a specialist immunization facility. Two hundred children were seen of whom 199 were immunized without any adverse effect; one child had an anaphylactic reaction. The proportion experiencing an anaphylactic reaction was 0.5% (95% CI 0.01-2.75%). It is believed that a history of egg protein allergy should no longer be regarded as a contra-indication to vaccination. Skin testing prior to measles immunization should, however, continue.

Publication types

  • Clinical Trial

MeSH terms

  • Anaphylaxis / etiology
  • Child
  • Child, Preschool
  • Egg Proteins, Dietary / adverse effects*
  • Female
  • Food Hypersensitivity / immunology*
  • Humans
  • Male
  • Measles / prevention & control
  • Measles Vaccine / adverse effects*
  • Measles Vaccine / immunology*
  • Skin Tests


  • Egg Proteins, Dietary
  • Measles Vaccine