The Pharynx of the Nematode Ascaris Suum: Structure and Function

Acta Biol Hung. 1995;46(2-4):195-204.

Abstract

The pharyngeal muscle of nematodes consists of a syncytium of radial muscle whereby feeding occurs by the process of pharyngeal pumping. It is believed that the pumping behaviour of the pharynx may be partly controlled by the enteric nervous system (ENS), a component of the nematode nervous system which is associated predominantly with the pharynx. The distribution of serotoninergic and peptidergic (especially SALMF-amide-like) immunostaining is widespread in the ENS of Ascaris, being localized within the lateral and dorsal pharyngeal nerve tracts, the pharyngeal commissures, the nerve plexuses and associated nerve cells and fibres. Immunostaining for serotonin (5-HT) was only localized within the ENS. This paper also describes a method to enable in vitro pharmacological studies on the Ascaris pharynx. The effects of "classical" neurotransmitters and native nematode peptides on pharyngeal pumping behaviour in Ascaris have been investigated. The function of the pharynx in Ascaris is discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Ascaris suum / anatomy & histology*
  • Ascaris suum / physiology*
  • Enteric Nervous System / anatomy & histology
  • Enteric Nervous System / drug effects
  • Enteric Nervous System / physiology
  • Immunohistochemistry
  • Invertebrate Hormones / chemistry
  • Invertebrate Hormones / pharmacology
  • Neuropeptides / chemistry
  • Neuropeptides / pharmacology
  • Neurotransmitter Agents / pharmacology
  • Pharyngeal Muscles / anatomy & histology
  • Pharyngeal Muscles / drug effects
  • Pharyngeal Muscles / physiology
  • Pharynx / anatomy & histology*
  • Pharynx / innervation
  • Pharynx / physiology*
  • Serotonin / metabolism
  • Serotonin / pharmacology

Substances

  • Invertebrate Hormones
  • Neuropeptides
  • Neurotransmitter Agents
  • Serotonin