Quantitative estimations of five classes of immunoglobulin in inbred mouse strains

Immunology. 1977 Jun;32(6):861-6.


The age-dependent change of the levels of five classes of immunoglobulin in mouse serum were investigated. Between 3 and 12 months after birth, the major IgG subclass of BALB/c was IgG1, while that of C57BL/6 was IgG2b. This difference was the same in the sera from hyperimmunized or germ-free animals.

MeSH terms

  • Age Factors
  • Animals
  • Immunoglobulin A / analysis
  • Immunoglobulin G / analysis
  • Immunoglobulin M / analysis
  • Immunoglobulins / classification*
  • Mice
  • Mice, Inbred BALB C / immunology
  • Mice, Inbred C3H / immunology
  • Mice, Inbred C57BL / immunology
  • Mice, Inbred Strains / immunology*


  • Immunoglobulin A
  • Immunoglobulin G
  • Immunoglobulin M
  • Immunoglobulins