Assays for antibodies to varicella-zoster virus

Infect Dis Clin North Am. 1996 Sep;10(3):507-27. doi: 10.1016/s0891-5520(05)70311-1.


Anti-varicella-zoster virus serum antibody assays and their use in vaccine development are described. Of particular interest are FAMA and neutralization assays and the gpELISA. These and other assays are compared and summarized in terms of characteristics including biologic relevance, sensitivity, specificity, and suitability for different laboratory and clinical applications.

Publication types

  • Review

MeSH terms

  • Antibodies, Viral / analysis*
  • Antibodies, Viral / immunology
  • Antigens, Viral / immunology
  • Chickenpox / immunology
  • Chickenpox / prevention & control
  • Chickenpox / virology
  • Cross Reactions
  • Enzyme-Linked Immunosorbent Assay
  • Herpesvirus 3, Human / immunology*
  • Humans


  • Antibodies, Viral
  • Antigens, Viral