Parasympathetic activity in Friedrich's ataxia

F Pousset; H Kalotka; A Durr; R Isnard; P Lechat; J Y Le Heuzey; D Thomas; M Komajda

doi:10.1016/s0002-9149(97)89245-4

Parasympathetic activity in Friedrich's ataxia

Am J Cardiol. 1996 Oct 1;78(7):847-50. doi: 10.1016/s0002-9149(97)89245-4.

Authors

F Pousset¹, H Kalotka, A Durr, R Isnard, P Lechat, J Y Le Heuzey, D Thomas, M Komajda

Affiliation

¹ Department of Cardiology, Pitié-Saltpêtrière Hospital, Paris, France.

PMID: 8857499
DOI: 10.1016/s0002-9149(97)89245-4

Abstract

We compared 19 patients with Friedreich's ataxia, a progressive hereditary neuromuscular disorder, with 19 healthy age-matched subjects. During nighttime, patients had shorter mean RR and decreased heart rate variability parameters related to parasympathetic activity than healthy subjects, whereas no difference occurred during daytime.

Publication types

Clinical Trial
Controlled Clinical Trial
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Atrial Premature Complexes / complications
Atrial Premature Complexes / diagnostic imaging
Atrial Premature Complexes / physiopathology
Echocardiography
Female
Fourier Analysis
Friedreich Ataxia / complications
Friedreich Ataxia / physiopathology*
Heart Rate / physiology*
Hemodynamics / physiology
Humans
Hypertrophy, Left Ventricular / complications
Hypertrophy, Left Ventricular / diagnostic imaging
Hypertrophy, Left Ventricular / physiopathology
Male
Middle Aged
Parasympathetic Nervous System / physiopathology*