Abstract
APECED, an autosomal recessive disease manifests itself as a widely variable combination of three groups of components: 1) autoimmune destruction of tissues, predominantly endocrine glands, 2) chronic superficial candidiasis, and 3) ectodermal dystrophy. Clinical and basic information obtained from Finnish series of 72 patients is reviewed.
MeSH terms
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Addison Disease / immunology
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Adolescent
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Adult
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Autoimmunity / immunology
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Candidiasis / immunology
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Child
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Child, Preschool
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Diabetes Mellitus, Type 1 / immunology
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Female
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Humans
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Hypoparathyroidism / immunology
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Hypothyroidism / immunology
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Incidence
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Infant
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Male
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Middle Aged
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Polyendocrinopathies, Autoimmune / genetics
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Polyendocrinopathies, Autoimmune / immunology*