Variations in the clinical course of submacular hemorrhage

Am J Ophthalmol. 1996 Oct;122(4):486-93. doi: 10.1016/s0002-9394(14)72107-5.


Purpose: To assess variations in the clinical course of submacular hemorrhages.

Methods: We reviewed fundus photography charts taken of patients during a 27-month period. Thirty-one eyes of 31 patients with submacular hemorrhages under the foveal avascular zone were reviewed.

Results: In 20 of the eyes, the underlying etiology was age-related macular degeneration (ARMD). The other 11 eyes had various underlying conditions, including macroaneurysms (two), presumed ocular histoplasmosis syndrome (two), trauma (one), Valsalva's retinopathy (one), idiopathic central serous choroidopathy (one), diabetic retinopathy (two), central retinal vein occlusion (one), and choroidal rupture (one). Of the eyes with ARMD (mean follow-up, 29 months), eight (40%) of 20 showed an improvement in visual acuity (> or = 2 Snellen lines), six (30%) of 20 had a final visual acuity of 20/80 or better, and three (15%) had a final visual acuity of 20/40 or better (range, 20/25 to 20/80). Of the eyes without ARMD (mean follow-up, 29 months), five (45) of 11 had an improvement in visual acuity and five (45%) of 11 attained a final visual acuity of 20/40 or better (range, 20/20 to 20/40). The best predictive factor for poor final visual acuity was the presence of a subretinal neovascular membrane.

Conclusions: Patients with submacular hemorrhage may have spontaneous improvement in visual acuity without surgery. Patients without subretinal neovascular membranes had a better visual improvement rate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Choroid Diseases / complications
  • Female
  • Follow-Up Studies
  • Fundus Oculi
  • Humans
  • Macula Lutea / physiopathology*
  • Male
  • Middle Aged
  • Photography
  • Retinal Diseases / complications
  • Retinal Hemorrhage / etiology
  • Retinal Hemorrhage / physiopathology*
  • Retrospective Studies
  • Visual Acuity / physiology