CENSOR--a program for identification and elimination of repetitive elements from DNA sequences

Comput Chem. 1996 Mar;20(1):119-21. doi: 10.1016/s0097-8485(96)80013-1.

Abstract

CENSOR is a program designed to identify and eliminate fragments of DNA sequences homologous to any chosen reference sequences, in particular to repetitive elements. CENSOR is based on two principal algorithms of Smith & Waterman (1981) [J. Mol. Biol. 147, 195] and Wilbur & Lipman (1983) [Proc. Natl. Acad. Sci. U.S.A. 80, 726]. It includes several pre-set sensitivity levels based on both biological and statistical criteria which help to distinguish between aligned pairs of homologous and non-homologous sequences. CENSOR has been implemented in C/C + + in the SUN/UNIX environment.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms
  • Base Sequence
  • Computer Communication Networks
  • Computers
  • Databases, Factual
  • Molecular Sequence Data
  • Repetitive Sequences, Nucleic Acid / genetics*
  • Sequence Alignment
  • Sequence Analysis
  • Software