Optimizing synaptic conductance calculation for network simulations

Neural Comput. 1996 Apr 1;8(3):501-9. doi: 10.1162/neco.1996.8.3.501.

Abstract

High computational requirements in realistic neuronal network simulations have led to attempts to realize implementation efficiencies while maintaining as much realism as possible. Since the number of synapses in a network will generally far exceed the number of neurons, simulation of synaptic activation may be a large proportion of total processing time. We present a consolidating algorithm based on a recent biophysically-inspired simplified Markov model of the synapse. Use of a single lumped state variable to represent a large number of converging synaptic inputs results in substantial speed-ups.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms
  • Axons / physiology
  • Computer Simulation
  • Markov Chains
  • Neural Networks, Computer*
  • Synapses / physiology*
  • Synaptic Transmission / physiology*