Risperidone antagonism of self-mutilation in a Lesch-Nyhan patient

Prog Neuropsychopharmacol Biol Psychiatry. 1996 Jul;20(5):793-800. doi: 10.1016/0278-5846(96)00059-0.

Abstract

1. The case is described of a 28-year old male with a diagnosis of Lesch-Nyhan syndrome. 2. Chronic treatment with the atypical neuroleptic risperidone at 4 mg daily has maintained a significant reduction in occurrence of self-mutilation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dopamine Antagonists / therapeutic use*
  • Humans
  • Lesch-Nyhan Syndrome / complications
  • Lesch-Nyhan Syndrome / drug therapy*
  • Lesch-Nyhan Syndrome / psychology
  • Male
  • Risperidone / therapeutic use*
  • Self Mutilation / drug therapy*
  • Self Mutilation / etiology

Substances

  • Dopamine Antagonists
  • Risperidone