Extraribosomal functions of ribosomal proteins

Trends Biochem Sci. 1996 May;21(5):164-5.


The discovery of DNA-binding motifs in ribosomal proteins has led to the conjecture that the transition of the ribosome from an RNA to an RNP machine occurred by adding pre-existing proteins. Supportive, but circumstantial, evidence for the hypothesis is adduced from the finding that many ribosomal proteins have a second function apart from the particle. These extraribosomal functions are enumerated.

MeSH terms

  • Biological Evolution*
  • DNA-Binding Proteins
  • Eukaryotic Cells
  • Prokaryotic Cells
  • Ribosomal Proteins / genetics*
  • Ribosomes


  • DNA-Binding Proteins
  • Ribosomal Proteins