Abstract
To deliver optimal radioiodine activity in hemodialyzed patients with thyroid carcinoma, the behavior of radioiodine was followed during six treatments. During hemodialysis, blood activity decreases with a half-life of 3.4 +/- 0.5, (1SD) h. The whole body dose was calculated from the total activity determined during 10 days after 131I administration. A reasonable strategy may consist in delivering 25% of the currently prescribed activity (925 MBq-25 mCi) and to perform the first dialysis session after 24 h to reduce total body irradiation.
MeSH terms
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Adult
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Carcinoma, Papillary / complications*
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Carcinoma, Papillary / radiotherapy*
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Fatal Outcome
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Female
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Graft Rejection / physiopathology
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Humans
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Hypertension, Renovascular / complications
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Iodine Radioisotopes / blood
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Iodine Radioisotopes / therapeutic use
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Kidney Failure, Chronic / complications*
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Kidney Failure, Chronic / therapy
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Kidney Transplantation / physiology
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Lymphatic Metastasis
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Middle Aged
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Neoplasm Metastasis
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Pancreas Transplantation / physiology
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Radiation Dosage
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Renal Dialysis*
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Thyroid Neoplasms / complications*
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Thyroid Neoplasms / radiotherapy*
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Thyroidectomy
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Whole-Body Counting