MR imaging of multiple sclerosis simulating brain tumor

Clin Imaging. 1996 Jul-Sep;20(3):171-7. doi: 10.1016/0899-7071(95)00012-7.


Multiple sclerosis may sometimes present as a mass lesion that is indistinguishable from brain tumor both clinically and radiologically. We describe two cases of multiple sclerosis simulating brain tumor on computed tomography (CT) scans and magnetic resonance (MR) images, one of which was proved and another was suggestive to be demyelinating disease by biopsy. Steroid therapy produced regression of the lesions of MR images and CT scans. Our cases and others in the literature suggest strategies for detecting multiple sclerosis presenting as a mass lesion.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Adult
  • Brain Neoplasms / complications
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / drug therapy
  • Demyelinating Diseases / complications
  • Demyelinating Diseases / diagnosis
  • Demyelinating Diseases / drug therapy
  • Diagnosis, Differential
  • Follow-Up Studies
  • Glucocorticoids / therapeutic use
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Multiple Sclerosis / complications
  • Multiple Sclerosis / diagnosis*
  • Multiple Sclerosis / drug therapy
  • Tomography, X-Ray Computed


  • Glucocorticoids