Antisense oligonucleotides as inhibitors of signal transduction: development from research tools to therapeutic agents

Biochem Soc Trans. 1996 Aug;24(3):623-9. doi: 10.1042/bst0240623.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Clinical Trials as Topic
  • Culture Techniques
  • Gene Targeting
  • Humans
  • Isoenzymes / genetics
  • Oligonucleotides, Antisense / genetics
  • Oligonucleotides, Antisense / pharmacokinetics
  • Oligonucleotides, Antisense / pharmacology*
  • Protein Kinase C / genetics
  • Protein Kinase C-alpha
  • Protein Serine-Threonine Kinases / genetics
  • Proto-Oncogene Proteins / genetics
  • Proto-Oncogene Proteins c-raf
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • Signal Transduction / drug effects*
  • Signal Transduction / genetics

Substances

  • Isoenzymes
  • Oligonucleotides, Antisense
  • Proto-Oncogene Proteins
  • RNA, Messenger
  • Protein Serine-Threonine Kinases
  • Proto-Oncogene Proteins c-raf
  • PRKCA protein, human
  • Protein Kinase C
  • Protein Kinase C-alpha