Loss of Y-cells in the lateral geniculate nucleus of monocularly deprived tree shrews

Science. 1977 Aug 19;197(4305):784-6. doi: 10.1126/science.887922.


In tree shrews (Tupaia glis) reared with one eye closed, Y-cells were almost entirely absent in the binocular segment of the lateral geniculate laminae receiving input from the deprived eye. Y-cells were found in the monocular segment of these laminae, and in the binocular segment of the laminae with input from the normal eye. X-cells were present in both the deprived and normal laminae and appeared unaffected by the deprivation. A number of abnormal cells were also found, and these were located primarily in the binocular segment where Y-cells were absent.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Geniculate Bodies / cytology*
  • Geniculate Bodies / growth & development
  • Shrews / anatomy & histology*
  • Visual Pathways / cytology*
  • Visual Pathways / growth & development
  • Visual Perception*