Explaining discrepant mortality results between primary percutaneous transluminal coronary angioplasty and thrombolysis for acute myocardial infarction

Am J Cardiol. 1996 Oct 15;78(8):934-9. doi: 10.1016/s0002-9149(96)00470-5.


Differing relative outcomes in randomized versus registry studies comparing primary angioplasty with thrombolytic therapy for acute myocardial infarction suggest a clinical paradox. A predictive model based on differences in 5 treatment-related factors, including time to therapy, patency success, and angioplasty experience, suggests that relative outcomes may indeed vary, depending on the clinical setting in which therapy is given.

Publication types

  • Editorial

MeSH terms

  • Algorithms
  • Angioplasty, Balloon, Coronary / mortality*
  • Hospital Mortality
  • Humans
  • Myocardial Infarction / mortality*
  • Myocardial Infarction / therapy*
  • Randomized Controlled Trials as Topic
  • Registries
  • Thrombolytic Therapy / mortality*
  • Time Factors
  • Treatment Outcome