Studies on the effect of organophosphorus pesticide phosalone on mouse immune system

S H Kowalczyk-Bronisz; J Kotz; B Bubak; M Pregiel

Studies on the effect of organophosphorus pesticide phosalone on mouse immune system

Arch Vet Pol. 1994;34(3-4):221-30.

Authors

S H Kowalczyk-Bronisz¹, J Kotz, B Bubak, M Pregiel

Affiliation

¹ Department of Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.

PMID: 8891176

Abstract

The effect of an organophosphorus pesticide-phosalone on some parameters of humoral and cellular immunologic response in mice was investigated. Haematological and morphological examinations were made parallelly. It was found that immunotropic effect of phosalone was a reversible process.

MeSH terms

Adrenal Glands / drug effects
Adrenal Glands / pathology
Animals
Antibody Formation / drug effects
Body Weight / drug effects
Female
Graft vs Host Reaction / immunology*
Hypersensitivity, Delayed*
Immunity, Cellular / drug effects
Insecticides / toxicity*
Interleukin-1 / biosynthesis
Lethal Dose 50
Leukocyte Count / drug effects
Lymph Nodes / drug effects
Lymph Nodes / pathology
Lymphocyte Transfusion
Macrophages, Peritoneal / drug effects
Macrophages, Peritoneal / immunology*
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Organ Size / drug effects
Organothiophosphorus Compounds / toxicity*
Rosette Formation
Spleen / drug effects
Spleen / pathology
Thymus Gland / drug effects
Thymus Gland / pathology

Substances

Insecticides
Interleukin-1
Organothiophosphorus Compounds
phosalone