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Review
. 1996 Oct 31;383(6603):787-93.
doi: 10.1038/383787a0.

Functional Diversity of Helper T Lymphocytes

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Review

Functional Diversity of Helper T Lymphocytes

A K Abbas et al. Nature. .

Abstract

The existence of subsets of CD4+ helper T lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for understanding the heterogeneity of normal and pathological immune responses. Defining the cellular and molecular mechanisms of helper-T-cell differentiation should lead to rational strategies for manipulating immune responses for prophylaxis and therapy.

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