The role of p53 loss in genomic instability and tumor progression in a murine mammary cancer model

Prog Clin Biol Res. 1996:395:1-11.

Authors

L A Donehower¹, L A Godley, C M Aldaz, R Pyle, Y P Shi, D Pinkel, J Gray, A Bradley, D Medina, H E Varmus

Affiliation

¹ Division of Molecular Virology, Baylor College of Medicine, Houston, TX 77030, USA.

PMID: 8895979

No abstract available

Publication types

Review

MeSH terms

Aneuploidy
Animals
Cell Transformation, Neoplastic / genetics
Crosses, Genetic
Disease Progression
Female
Gene Targeting
Genes, p53*
Male
Mammary Neoplasms, Experimental / genetics*
Mammary Neoplasms, Experimental / pathology
Mice
Mice, Knockout
Mice, Transgenic
Neoplasms, Experimental / genetics
Proto-Oncogene Proteins / genetics
Tumor Suppressor Protein p53 / deficiency*
Tumor Suppressor Protein p53 / physiology
Wnt Proteins
Zebrafish Proteins*

Substances

Proto-Oncogene Proteins
Tumor Suppressor Protein p53
Wnt Proteins
Zebrafish Proteins