Elevated serum IgE and IgG4 in patients with atopic dermatitis

Br J Dermatol. 1977 Jul;97(1):59-63. doi: 10.1111/j.1365-2133.1977.tb15428.x.


The quantitative measurement of the IgE and IgG subclass levels in the sera of 29 patients with atopic dermatitis has revealed significantly elevated levels of IgE and IgG4 in a relatively high proportion of patients with this condition compared to non-atopic patients with warts and to a group of normal volunteers studied previously. The possible significance of these observations is discussed in relation to current evidence suggesting the involvement of IgG4 in certain immediate-type hypersensitivity disorders.

MeSH terms

  • Adolescent
  • Adult
  • Dermatitis, Atopic / immunology*
  • Humans
  • Immunoglobulin E / analysis*
  • Immunoglobulin G / analysis*
  • Middle Aged
  • Warts / immunology


  • Immunoglobulin G
  • Immunoglobulin E