Advances in clinical pharmacology and therapeutics: endothelin

Br J Hosp Med. 1996 Oct;56(7):360-4.

Abstract

Endothelin-1, a potent endothelium-derived 21-amino acid vasoconstrictor peptide was only discovered relatively recently. Antagonism of its actions may provide an important new approach to the modulation of cardiac and vascular function.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cardiovascular Diseases / physiopathology
  • Endothelin Receptor Antagonists
  • Endothelin-1 / physiology
  • Endothelins / antagonists & inhibitors
  • Endothelins / physiology*
  • Humans
  • Renal Insufficiency / physiopathology

Substances

  • Endothelin Receptor Antagonists
  • Endothelin-1
  • Endothelins