Abnormal development of the locomotor activity in yellow larvae of Drosophila: a cuticular defect?

Genetica. 1996 Mar;97(2):205-10. doi: 10.1007/BF00054627.

Abstract

The yellow (y) mutation of Drosophila melanogaster affects the development of behavior and morphology. We have analyzed some behavioral and morphological parameters during the development of y mutants. Wild-type third instar larvae move in straighter paths than larvae of the same age homozygous for the y mutation. At 96 h of age, the tracks of y larvae have 10 times as many loops as tracks of wild-type larvae, and at 120 h of age, y larvae show bending behavior about 2.5 times more frequently than do wild-type. Consequently, they do not disperse as much as wild-type larvae. Concomitant with the behavioral changes, the larvae present a defect in the morphology of large chaetae in the larval denticle belts, particularly of 2nd and 3rd instars, both with light and scanning electron microscopes. These results suggest that a cuticular defect is probably involved in the abnormal locomotor activity observed in y larvae of Drosophila melanogaster.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Drosophila Proteins*
  • Drosophila melanogaster / embryology*
  • Drosophila melanogaster / genetics
  • Female
  • Homozygote
  • Insect Hormones / genetics*
  • Larva / growth & development
  • Larva / physiology*
  • Larva / ultrastructure
  • Microscopy, Electron, Scanning
  • Motor Activity / genetics*

Substances

  • Drosophila Proteins
  • Insect Hormones
  • y protein, Drosophila