Human papillomavirus vaccines for cervical cancer

Curr Opin Immunol. 1996 Oct;8(5):643-50. doi: 10.1016/s0952-7915(96)80080-x.

Abstract

The association of carcinoma of the uterine cervix with human papillomavirus indicates that vaccine strategies which target the virus could be useful in the control of disease progression. Recent advances have centered on directing the immune response to prevention of infection, to virus-infected (but nontransformed) cells and to virally transformed cells, with favourable results.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Antigens, Viral, Tumor / genetics
  • Cancer Vaccines / pharmacology*
  • Cell Transformation, Viral
  • Clinical Trials as Topic
  • Disease Models, Animal
  • Female
  • Humans
  • Papillomaviridae / genetics
  • Papillomaviridae / immunology*
  • Papillomaviridae / pathogenicity
  • Papillomavirus Vaccines*
  • Uterine Cervical Neoplasms / etiology
  • Uterine Cervical Neoplasms / prevention & control
  • Uterine Cervical Neoplasms / therapy*
  • Viral Vaccines / pharmacology*
  • Virus Replication / immunology

Substances

  • Antigens, Viral, Tumor
  • Cancer Vaccines
  • Papillomavirus Vaccines
  • Viral Vaccines