A case of kala-azar diagnosed by bone marrow aspiration

Malays J Pathol. 1995 Jun;17(1):39-41.


A 35-year-old man from Bangladesh, who had been in Malaysia for approximately a year, was extensively investigated for more than two months in a state hospital for pyrexia with hepatosplenomegaly. However, no obvious cause of his illness was found. He was treated with multiple antibiotics with no resolution of pyrexia and hepatosplenomegaly. He was later referred to the Haematology Unit, Universiti Kebangsaan Malaysia for further assessment as a case of lymphoma. On carefully reviewing his bone marrow aspirate smears, the diagnosis of leishmaniasis (kala-azar) was finally made. The patient responded to treatment with pentamidine.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy, Needle
  • Bone Marrow / parasitology*
  • Bone Marrow / pathology*
  • Bone Marrow Examination
  • Diagnosis, Differential
  • Fever of Unknown Origin / etiology*
  • Humans
  • Leishmaniasis, Visceral / pathology*
  • Lymphoma / diagnosis
  • Macrophages / parasitology
  • Macrophages / pathology
  • Male