Neuroendocrine carcinoma of the larynx

J R Coll Surg Edinb. 1996 Oct;41(5):333-5.


Neuroendocrine carcinomas (NEC) of the larynx are rare. The key to diagnosis is therefore an increased awareness of such lesions amongst otolaryngologists and pathologists. A precise histological diagnosis is crucial, as the management is different for each NEC sub-type. Advances in immunohistochemistry have been a great help in this respect. We report a typical case of large cell NEC (atypical carcinoid) and highlight the clinical pointers to the histological diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Neuroendocrine / classification
  • Carcinoma, Neuroendocrine / pathology*
  • Carcinoma, Neuroendocrine / secondary
  • Carcinoma, Neuroendocrine / therapy
  • Combined Modality Therapy
  • Humans
  • Laryngeal Neoplasms / pathology*
  • Laryngeal Neoplasms / therapy
  • Larynx / pathology*
  • Male
  • Middle Aged
  • Skin Neoplasms / secondary