Magnesium taurate for the prevention and treatment of pre-eclampsia/eclampsia

Med Hypotheses. 1996 Oct;47(4):269-72. doi: 10.1016/s0306-9877(96)90065-1.

Abstract

The use of parenteral magnesium sulfate for the management of pre-eclampsia/eclampsia is well established. In striking analogy to the effects of hypermagnesemia, taurine has antivasospastic, antihypertensive, platelet-stabilizing, anticonvulsant and hypoxia-protective properties. Thus parenteral magnesium taurate can reasonably be proposed as a superior alternative to magnesium sulfate in the treatment of pre-eclampsia; administered orally as a component of prenatal supplementation, magnesium taurate might well have both preventive and therapeutic value in this syndrome. In the light of the hypoxia-protective actions of both magnesium and taurine, such supplementation might also protect fetuses experiencing temporary perinatal asphyxia, lessening the risk of cerebral palsy.

MeSH terms

  • Eclampsia / drug therapy*
  • Eclampsia / prevention & control*
  • Female
  • Fetus
  • Food, Fortified
  • Humans
  • Magnesium / therapeutic use
  • Models, Theoretical
  • Pre-Eclampsia / drug therapy*
  • Pre-Eclampsia / prevention & control*
  • Pregnancy
  • Taurine / administration & dosage
  • Taurine / therapeutic use

Substances

  • Taurine
  • Magnesium