Enterobacter sepsis in the newborn--a growing problem in Karachi

J Hosp Infect. 1996 Nov;34(3):211-6. doi: 10.1016/s0195-6701(96)90068-7.


Enterobacter sepsis is commonly recognized as a hospital-acquired infection in childhood. In a five year prospective surveillance of neonatal sepsis at the Aga Khan University Hospital in Karachi, we identified Enterobacter sepsis in 28/292 (10%) cases, with an incidence of 0.7 per thousand births among inborn infants. There was no significant difference in predisposing factors and clinical features between Enterobacter and other infections. Approximately half (47%) of Enterobacter infections presented within 72 h of birth and the associated mortality was 21%. Increasing resistance to commonly used first- and second-line antibiotics over the last five years was noted. Enterobacter infections are emerging as significant pathogens among cases of neonatal sepsis in Karachi.

MeSH terms

  • Case-Control Studies
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Cross Infection / prevention & control
  • Drug Resistance, Microbial
  • Enterobacteriaceae Infections / epidemiology*
  • Enterobacteriaceae Infections / prevention & control
  • Humans
  • Incidence
  • Infant, Newborn
  • Infection Control / methods
  • Intensive Care Units, Neonatal*
  • Pakistan / epidemiology
  • Prospective Studies
  • Risk Factors
  • Sepsis / microbiology*
  • Sepsis / prevention & control