Evaluating quality-of-life and health status instruments: development of scientific review criteria

Clin Ther. 1996 Sep-Oct;18(5):979-92. doi: 10.1016/s0149-2918(96)80054-3.


The Medical Outcomes Trust is a depository and distributor of high-quality, standardized, health outcomes measurement instruments to national and international health communities. Every instrument in the Trust library is reviewed by the Scientific Advisory Committee against a rigorous set of eight attributes. These attributes consist of the following: (1) conceptual and measurement model; (2) reliability; (3) validity; (4) responsiveness; (5) interpretability; (6) respondent and administrative burden; (7) alternative forms; and (8) cultural and language adaptations. In addition to a full description of each attribute, we discuss uses of these criteria beyond evaluation of existing instruments and lessons learned in the first few rounds of instrument review against these criteria.

MeSH terms

  • Health Status Indicators*
  • Health Status*
  • Humans
  • Quality of Life*
  • Reproducibility of Results