Randomized controlled trials in industrial low back pain relating to return to work. Part 2. Discogenic low back pain

Arch Phys Med Rehabil. 1996 Nov;77(11):1189-97. doi: 10.1016/s0003-9993(96)90147-1.


The purpose of this review was to determine the efficacy of treatments for discogenic low back pain (LBP) by examining all randomized controlled trials (RCTs) of discogenic LBP published in the English language literature between 1975 and 1993 with "return to work" (RTW) as the end point. From more than 4,000 LBP citations, nearly 600 articles were initially reviewed; 35 studies met our selection criteria. Twenty-two studies were discussed in Part 1 (Acute Interventions) or will be discussed in Part 3 (Chronic Interventions). In this review, of 13 RCTs assessing interventions for LBP with sciatica, 9 were appropriate for their focus on, and radiologic confirmation of, discogenic LBP. The treatments assessed included chemonucleolysis, surgical discectomy, and epidural steroid injection. A 26-point system to assess the quality of methodologic rigor was used for each article. Our literature survey found a need for additional studies comparing surgery, conservative care, epidural steroids, traction, and other approaches to determine their individual effects for RTW after discogenic disease.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Diskectomy
  • Humans
  • Injections, Epidural
  • Intervertebral Disc Chemolysis
  • Intervertebral Disc Displacement / rehabilitation
  • Intervertebral Disc Displacement / therapy*
  • Low Back Pain / rehabilitation*
  • Occupational Diseases / rehabilitation*
  • Randomized Controlled Trials as Topic
  • Work


  • Adrenal Cortex Hormones