[Choroidal vascular lesions in serous retinal detachment viewed with indocyanine green angiography]

Nippon Ganka Gakkai Zasshi. 1996 Oct;100(10):817-24.
[Article in Japanese]


In serous retinal detachment due to damaged retinal pigment epithelium (RPE), fluorescein angiography shows dye leakage into the subretinal space from the choroid. We performed indocyanine green (ICG) angiography in 110 eyes with serous retinal detachment comprising 71 eyes with central serous chorioretinopathy (CSC), 19 with bullous retinal detachment, 18 with Harada's disease, and 2 with toxemia of pregnancy. Choroidal tissue staining was present around the site of subretinal leakage in late-phase ICG angiograms from 63 eyes with CSC and 18 with bullous retinal detachment. ICG angiography also showed leakage from choroidal vessels in 16 eyes with Harada's disease and 2 with toxemia of pregnancy. As a common feature, ICG angiography showed choroidal vascular hyperpermeability in various types of serous retinal detachment. Choroidal circulation was delayed in Harada's disease and toxemia of pregnancy. Choroidal hypoperfusion and hyperpermeability of choroidal vessels probably contribute to the damage of RPE, and choroidal vascular hyperpermeability probably provides fluid pressure to move fluid into the subretinal space from the choroid.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Capillary Permeability
  • Choroid / blood supply*
  • Female
  • Fluorescein Angiography*
  • Humans
  • Indocyanine Green
  • Male
  • Pre-Eclampsia / complications
  • Pregnancy
  • Retinal Detachment / diagnosis
  • Retinal Detachment / pathology*
  • Uveomeningoencephalitic Syndrome / complications


  • Indocyanine Green