Ion channel associated proteins

Curr Opin Neurobiol. 1996 Oct;6(5):602-8. doi: 10.1016/s0959-4388(96)80091-2.


Neuronal ion channels are directly associated in vivo with a wide variety of proteins. New classes of channel-associated proteins have been identified recently, including the PSD-95/SAP90 family of channel-clustering molecules and components of the synaptic vesicle release machinery. Recent findings suggest that non-pore-forming subunits of ion channels may also have cell biological functions independent of their effects on channel electrophysiological properties.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Calcium Channels / physiology
  • Disks Large Homolog 4 Protein
  • Humans
  • Intracellular Signaling Peptides and Proteins
  • Ion Channel Gating
  • Ion Channels / pharmacology*
  • Mammals
  • Membrane Proteins / physiology
  • Models, Neurological
  • Nerve Tissue Proteins / physiology*
  • Neurons / physiology*
  • Neurotransmitter Agents / physiology
  • Qa-SNARE Proteins


  • Calcium Channels
  • DLG4 protein, human
  • Disks Large Homolog 4 Protein
  • Intracellular Signaling Peptides and Proteins
  • Ion Channels
  • Membrane Proteins
  • Nerve Tissue Proteins
  • Neurotransmitter Agents
  • Qa-SNARE Proteins
  • postsynaptic density proteins