Paraquat poisoning: significance of plasma-paraquat concentrations

Lancet. 1979 Aug 18;2(8138):330-2. doi: 10.1016/s0140-6736(79)90345-3.

Abstract

Plasma-paraquat concentrations were measured in 79 patients who had ingested liquid or granular weedkillers containing paraquat. At any given time after ingestion, the plasma-paraquat concentrations in the patients who died usually exceeded those in the survivors. It is suggested that measurement of plasma-paraquat concentrations is useful in assessing the severity and predicting the outcome of poisoning. Patients whose plasma concentrations do not exceed 2.0, 0.6, 0.3, 0.16, and 0.1 mg/l at 4, 6, 10, 16, and 24 h respectively are likely to survive.

Publication types

  • Comparative Study

MeSH terms

  • Accidents
  • Administration, Oral
  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Middle Aged
  • Paraquat / administration & dosage
  • Paraquat / blood
  • Paraquat / poisoning*
  • Prognosis
  • Suicide, Attempted
  • Time Factors

Substances

  • Paraquat