Antibiotic resistance: counting the cost

Curr Biol. 1996 Oct 1;6(10):1219-21. doi: 10.1016/s0960-9822(96)00700-2.


Acquisition of drug resistance should impose a cost on bacteria. Recent studies, however, suggest that natural selection acts to reduce, or eliminate, the growth disadvantage of resistant bacteria, making it difficult to reverse the high levels of antibiotic resistance currently found in hospitals and the community.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Bacteria / drug effects
  • Drug Resistance, Microbial*
  • Hospitals
  • Humans
  • Selection, Genetic


  • Anti-Bacterial Agents